Mechanism action of Calcium carbonate
Calcium carbonate is a basic inorganic salt that acts by neutralizing
hydrochloric acid in gastric secretions. It also inhibits the action of
pepsin by increasing the pH and via adsorption. Cytoprotective effects
may occur through increases in bicarbonate ion (HCO3-)
and prostaglandins. Neutralization of hydrochloric acid results in the
formation of calcium chloride, carbon dioxide and water. Approximately
90% of calcium chloride is converted to insoluble calcium salts (e.g.
calcium carbonate and calcium phosphate).
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