Mechanism action of Ceftriaxone
Ceftriaxone works by inhibiting the mucopeptide synthesis in the
bacterial cell wall. The beta-lactam moiety of Ceftriaxone binds to
carboxypeptidases, endopeptidases, and transpeptidases in the bacterial
cytoplasmic membrane. These enzymes are involved in cell-wall synthesis
and cell division. By binding to these enzymes, Ceftriaxone results in
the formation of of defective cell walls and cell death.
No comments:
Post a Comment