Mechanism action of Bimatoprost
Bimatoprost is believed to lower intraocular pressure (IOP) in humans by
increasing outflow of aqueous humor through both the trabecular
meshwork and uveoscleral routes. Bimatoprost reduces the pressure in the
eye by mimicking the action of a naturally-occuring prostaglandin.
Prostaglandins are a group of chemicals found in many places in the
body. In the eye, they increase the drainage of the aqueous humour out
of the eyeball. Bimatoprost is a synthetic compound related to one of
the natural prostaglandins, and works by increasing the drainage of
aqueous humour out of the eyeball. Bimatoprost may also lower the rate
of aqueous formation in the eye. Both these effects decrease the
pressure within the eye.
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