Mechanism action of Benzphetamine
Although the mechanism of action of the sympathomimetic appetite
suppressants in the treatment of obesity is not fully known, these
medications have pharmacological effects similar to those of
amphetamines. Amphetamine and related sympathomimetic medications (such
as benzphetamine) are thought to stimulate the release of norepinephrine
and/or dopamine from storage sites in nerve terminals in the lateral
hypothalamic feeding center, thereby producing a decrease in appetite.
This release is mediated by the binding of benzphetamine to centrally
located adrenergic receptors.
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