Mechanism action of Biperiden
Parkinsonism is thought to result from an imbalance between the
excitatory (cholinergic) and inhibitory (dopaminergic) systems in the
corpus striatum. The mechanism of action of centrally active
anticholinergic drugs such as biperiden is considered to relate to
competitive antagonism of acetylcholine at cholinergic receptors in the
corpus striatum, which then restores the balance.
No comments:
Post a Comment