Mechanism action of Bromfenac
The mechanism of its action is thought to be due to its ability to block
prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.
Prostaglandins have been shown in many animal models to be mediators of
certain kinds of intraocular inflammation. In studies performed in
animal eyes, prostaglandins have been shown to produce disruption of the
blood-aqueous humor barrier, vasodilation, increased vascular
permeability, leukocytosis, and increased intraocular pressure.
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