Mechanism action of Betaxolol
Betaxolol selectively blocks catecholamine stimulation of
beta(1)-adrenergic receptors in the heart and vascular smooth muscle.
This results in a reduction of heart rate, cardiac output, systolic and
diastolic blood pressure, and possibly reflex orthostatic hypotension.
Betaxolol can also competitively block beta(2)-adrenergic responses in
the bronchial and vascular smooth muscles, causing bronchospasm.
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